赵 忠


教授 博士生导师 现任中国细胞生物学会植物器官发生分会会长 2018-2022年教育部大学生物学课程教学指导委员会委员 中国植物生理与植物分子生物学会理事 中国科学院分子植物科学卓越创新中心研究员 安徽省细胞生物学会常务理事 中国科技大学生命科学国家级实验教学中心主任。

      1991年和1994年毕业于兰州大学生物系细胞生物学专业,分别获理学学士和硕士学位。2003年毕业于复旦大学生化系,获理学博士学位。20032005年赴法国国家科研中心(CNRS)植物分子生物学研究所(IBMP)从事博士后研究。20062009年,在德国马普(Max Planck)发育生物研究所从事博士后研究。20092011年,在海德堡大学干细胞生物学系工作。2011年加入中国科技大学生命科学学院。

赵忠教授主要从事植物干细胞和发育生物学研究,首次在高等真核生物中报道了组蛋白H336位赖氨酸甲基化的生物学功能,以及在干细胞中生长素和细胞分裂素相互作用控制干细胞微环境的分子机制。主要研究成果发表于 Nature, Nature Cell Biology, EMBO J, Development Cell, PNAS Plant Cell等学术期刊,4篇文章受到Faculty of 1000推荐和评价,1篇文章为 ESI高被引论文(Highly Cited Papers)

  

实验室主要研究兴趣:

1)植物干细胞 微环境建立和调控的分子机理。

2)植物干细胞的维持与分化的分子机制。

3)干细胞对发育和环境信号的整合与适应。

  

论文发表统计

ResearchID: https://publons.com/researcher/1661679/zhong-zhao

Scopus:  https://www.scopus.com/authid/detail.uri?authorId=55726118900

Researchgatehttps://www.researchgate.net/profile/Zhong_Zhao13

  

代表性学术论文:

1. Yang L, Wang HN, Hou XH, Zou YP, Han TS, Niu XM, Zhang J, Zhao Z, Todesco M, Balasubramanian S, Guo YL.Parallel Evolution of Common Allelic Variants Confers Flowering Diversity in Capsella rubella.

Plant Cell. 30(6): 1322-1336, 2018  https://www.ncbi.nlm.nih.gov/pubmed/29764984

2. Luo L, Zeng J, Wu H, Tian Z*, Zhao Z*. A Molecular Framework for Auxin-Controlled Homeostasis of Shoot Stem Cells in Arabidopsis.Mol Plant. 11(7), 899-913, 2018.https://www.ncbi.nlm.nih.gov/pubmed/29730265

3. Qu X, Zhao Z* and Tian Z*.ERECTA regulates cell elongation by activating auxin biosynthesis in Arabidopsis thaliana.

Front. Plant Sci. doi: 10.3389/fpls.2017.01688, 2017 https://www.ncbi.nlm.nih.gov/pubmed/29021806

4. Zeng J, Dong Z, Wu H, Tian Z, Zhao Z*.Redox regulation of plant stem cell fate.

EMBO J. 36, 2844-2855, 2017 (doi: 10.15252/embj.201695955, 2017) https://www.ncbi.nlm.nih.gov/pubmed/28838936

5. Yang ZB, Liu G, Liu J, Zhang B, Meng W, Müller B, Hayashi KI, Zhang X, Zhao Z, De Smet I, Ding Z. Synergistic action of auxin and cytokinin mediates aluminum-induced root growth inhibition in Arabidopsis.EMBO Rep. 18(7): 1213-1230, 2017

https://www.ncbi.nlm.nih.gov/pubmed/28600354

6. Wang J, Tian C, Zhang C, Shi B, Cao X, Zhang TQ, Zhao Z, Wang JW, Jiao Y. Cytokinin Signaling Activates WUSCHEL Expression during Axillary Meristem Initiation.Plant Cell. 29(6): 1373-1387, 2017

https://www.ncbi.nlm.nih.gov/pubmed/28576845

7. Cui Y, Rao S, Chang B, Wang X, Zhang K, Hou X, Zhu X, Wu H, Tian Z, Zhao Z, Yang C, Huang T. AtLa1 protein initiates IRES-dependent translation of WUSCHEL mRNA and regulates the stem cell homeostasis of Arabidopsis in response to environmental hazards.Plant Cell Environ. 38(10) :2098-114, 2015 https://www.ncbi.nlm.nih.gov/pubmed/25764476

8. Somorjai IM, Lohmann JU, Holstein TW, Zhao Z. Stem cells: a view from the roots.Biotechnol J. 7(6): 704-22, 2012

https://www.ncbi.nlm.nih.gov/pubmed/22581706

9. Zhao Z, Andersen SU, Ljung K, Dolezal K, Miotk A, Schultheiss SJ and Lohmann JU. Hormonal control of the shoot stem cell niche.Nature, 465: 1089-1092, 2010.http://www.ncbi.nlm.nih.gov/pubmed/20577215

10. Busch W, Miotk A, Ariel FD, Zhao Z, Forner J, Daum G, Suzaki T, Schuster C, Schultheiss SJ, Leibfried A, Haubeiß S, Ha N, Chan R and LohmannJU. Transcriptional control of a plant stem cell niche.Developmental Cell. 18, 841-853, 2010.http://www.ncbi.nlm.nih.gov/pubmed/20493817

11. Buechel S, Leibfried A, To JP, Zhao Z, Andersen SU, Kieber JJ, Lohmann JU. Role of A-type ARABIDOPSIS RESPONSE REGULATORS in meristem maintenance and regeneration.

Eur J Cell Biol. 89(2-3): 279-84, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20018401

12. Zhao Z, Zhu Y, Erhardt M, Ruan Y, Shen WH. A Non-canonical Transferred DNA Insertion at the BRI1 Locus in Arabidopsis thaliana,J Integr Plant Biol., 51(4): 367-73, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19341406

13. Andersen SU, Buechel S, Zhao Z, Ljung K, Novák O, Busch W, Schuster C, Lohmann JU. Requirement of B2-type cyclin-dependent kinases for meristem integrity in Arabidopsis thaliana,Plant Cell, 20(1): 88-100, 2008.   http://www.ncbi.nlm.nih.gov/pubmed/18223038

14. Xu L, Zhao Z, Dong A, Soubigou-Taconnat L, Renou JP, Steinmetz A, Shen WH. Di- and tri- but not monomethylation on histone H3 lysine 36 marks active transcription of genes involved in flowering time regulation and other processes in Arabidopsis thaliana.Mol Cell Biol., 28(4): 1348-60, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18070919

15. Feng X*, Zhao Z*, Tian Z*, Xu S, Luo Y, Cai Z, Wang Y, Yang J, Wang Z, Weng L, Chen J, Zheng L, Guo X, Luo J, Sato S, Tabata S, Ma W, Cao X, Hu X, Sun C, Luo D. Control of petal shape and floral zygomorphy in Lotus japonicus. Proc Natl Acad Sci U S A. 103(13): 4970-4975, 2006, (*co-first authors). http://www.ncbi.nlm.nih.gov/pubmed/16549774

16. Guo X, Zhao Z, Chen J, Hu X, Luo D. A putative CENTRORADIALIS/TERMINAL FLOWER 1-like gene, Ljcen1, plays a role in phase transition in Lotus japonicus.J Plant Physiol., 163(4): 436-44,2006.          http://www.ncbi.nlm.nih.gov/pubmed/16455357

17. Zhao Z, Yu Y, Meyer D, Wu C and Shen WH. Prevention of early flowering by expression of FLOWERING LOCUS C requires methylation of histone H3 K36, Nature Cell Biology, 7(12): 1256-60, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16299497

18. Dong ZC, Zhao Z, Liu CW, Luo JH, Yang J, Huang WH, Hu XH, Wang TL, Luo D. Floral patterning in Lotus japonicus.

            Plant Physiol., 137(4): 1272-82, 2005.   http://www.ncbi.nlm.nih.gov/pubmed/15824286

19. Luo JH, Yan J, Weng L, Yang J, Zhao Z, Chen JH, Hu XH, Luo D. Different expression patterns of duplicated PHANTASTICA-like genes in Lotus japonicus suggest their divergent functions during compound leaf development.

Cell Res. 2005, 15(8): 665-77, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16117856

20. Zhao Z and Shen WH. Plants contain a high number of proteins showing sequence similarity to the animal SUV39H family of histone methyltransferases.Ann.N.Y.Acad.Sci.1030: 661-669, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15659850

21. Hu.W, Zhang, S., Zhao Z, Sun. C., Zhao. Y. and Luo. D. The analysis of the structure and expression of OsTB1 gene in rice.

Journal of Plant Physiology and Molecular Biology, 29(6): 507-514, 2003

22. Zheng LY, Zhu XD, Qian Q, Zhao Z, Zhang JJ, Hu XH, Lin HX and Luo D, Morphological and gene location analysis on rice cl mutant.Chinese Science Bulletin, 48(3): 264-267, 2003

http://www.scichina.com:8080/kxtb/CN/abstract/abstract368626.shtml#

23. Zhao Z and Jia J-F. Selection of methionine-resistance variant of Medicago sativa.Acta Botanica Sinica. 39(10): 933-939, 1997 http://www.jipb.net/pubsoft/content/2/3402/39-10-8.pdf

24. Zhao Z and Jia J-F. Selection of methionine-resistance variant of Onobrychis viciaefolia Scop.

Acta Botanica Sinica. 38(4): 268-275, 1996 http://www.jipb.net/pubsoft/content/2/3432/38-4-4.pdf

25. Zhao Z, Lin H and Jia J-F. The accumulation of organic osmotica of the salt-tolerant calli under the NaCl stress in Onobrychis viciaefolia.Journal of Lanzhou University (Nature Sciences). 30(suppl.): 36-39, 1994

26. Zhao Z and Jia J-F. Selection of NaCl-tolerant cell line of Medicago sativa and Onobrychis viciaefolia and analysis of their physiological and biochemical characteristics. Journal of Lanzhou University (Nature Sciences). 28(3): 109-114, 1992

  

联系方式:

电话0551-63600640

传真: 0551-63600640

Emailzhzhao@ustc.edu.cn

  

招生招聘:

1,本科实习生、研究生:对发育生物学和植物学感兴趣。

2,博士后:有分子生物学,发育生物学或植物学相关背景,具备独立研究能力,作为第一作者发表过SCI论文。

  




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