2018.04.12 Wayne State University Dr. Leonard Lipovich 学术报告会
题目：Long Non-Coding RNA Genes: Primate-Specific Causes of Human Disease, Post-Genomic Targets for Precision Medicine.
报告人：Dr. Leonard Lipovich，Associate Professor，Wayne State University，USA
Leonard Lipovich, earned his B.A. (cum laude) in Genetics and Development from Cornell University (1998), and his Ph.D. in Genome Sciences from the University of Washington – Seattle (2003). He completed his postdoctoral training at the Genome Institute of Singapore, where he discovered the first long non-coding RNA (lncRNA) functional in mammalian stem cell pluripotency, and pioneered the concept of lncRNA evolutionary non-conservation, highlighting the abundance of primate-specific lncRNAs in humans. Dr. Lipovich joined Wayne State University (Detroit, Michigan) in 2007, and was promoted to associate professor with tenure in 2013. The Lipovich Lab was the first in the world to examine lncRNA translation in human cells using mass spectrometry, finding that most lncRNAs are not translated. In 2014, Dr. Lipovich received the U.S. National Institutes of Health (NIH) Director's New Innovator Award (USD $2,300,000). Dr. Lipovich interrogates the contribution of primate-specific lncRNAs to human cancer and metabolic disorders, using integrated computational and experimental approaches. He chaired the Keystone Symposium and the Royal Society International Scientific Meeting on lncRNAs in 2015. A CHARGE Consortium co-investigator, he participated in the ENCODE (Encyclopedia of DNA Elements) and FANTOM (Functional Annotation of Mammalian cDNA) Consortia. His goal is personalized, lncRNA-targeted post-genomic therapeutics.