特任教授，博士生导师。2021年加入中国科学与技术大学。摄食是人和动物最基本的生理需求，是生存的必要条件，摄食也与机体健康密切相关。过量摄食导致肥胖并诱发多种代谢性疾病，而适度饥饿节食则有利于机体健康，甚至延缓衰老。在过去几年中，团队聚焦于饥饿感知和饥饿调控免疫功能，通过运用多种神经技术，结合流式细胞术和疾病小鼠模型，发现了新的饥饿感知的神经机制，并初步揭示饥饿抑制自身免疫疾病的神经机制。发表学术论文20余篇，主要研究成果以通讯作者身份发表于Nature Neuroscience, Neuron等国际知名杂志上，引用1900余次，h-index 16，单篇最高引用470余次。中国神经科学学会应激分会委员，中国生理学会青年委员会委员，中国生理学会自主神经分会委员。
主要研究兴趣：
1）摄食行为的神经调控机制，
2）能量代谢的神经调控机制，
3）神经-免疫的互作机制。
代表性学术论文（#通讯作者）：
1、Liang Wang, Mingxiu Cheng, Yucheng Wang, Jing Chen, Faming Xie, Li-Hao Huang, Cheng Zhan#. Fasting-activated neurons regulate immune cell homing and suppress autoimmune diseases in mice. Nature Neuroscience (2024).
News and Views, Hunger guides immunity to friend versus foe. N. Or-Geva and L. Steinman, Nature Neuroscience (2024).
2、Jing Cai, Jing Chen, Joshua Ortiz-Guzman, Jessica Huang, Benjamin R Arenkiel, Yuchen Wang, Yan Zhang, Yuyan Shi, Qingchun Tong#, Cheng Zhan#. AgRP neurons are not indispensable for body weight maintenance in adult mice. Cell Reports (2023).
3、Meiqi Wang, Cheng Zhan#. Anatomical analysis of sensory ganglia in mice. Stress and Brain (2022).
4、Jing Chen, Chunli Li, Zhonghua Lu, Cheng Zhan#. Optimal Timing of a Commonly-Used Rabies Virus for Neural Recording and Manipulation. Neuroscience Bulletin (2022).
5、Jing Chen, Minxiu Cheng, Liang Wang, Lei Zhang, Dan Xu, Peng Cao, Fengchao Wang, Herbert Herzog, Sen Song, Cheng Zhan#. A vagal-NTS neural pathway that stimulates feeding. Current Biology (2020).
6、L. Mei, Y.Fan , M. Wang, X. Lv , C. Zhan#, E. Zhang#. Longitudinal in vivo recording of clock gene transcription in the brains of freely-moving mice. PNAS (2018). Selected for F1000Prime.
7、Z. Zhao, L. Wang, W. Gao, F. Hu, J. Zhang, Y. Ren, R. Lin, Q. Feng, M. Cheng, D. Ju, Q. Chi, D. Wang, S. Song, M. Luo and C. Zhan#. A Central Catecholaminergic Circuit Controls Blood Glucose Levels during Stress. Neuron(2017). Featured Article.
8、D. Wang, X. He, Z. Zhao, Q.Feng, R.Lin, Y. Sun, T. Ding, F. Xu #, M. Luo #, C. Zhan #. Whole-brain mapping of the direct inputs and axonal projections of POMC and AgRP neurons. Frontiers in Neuroanatomy(2015). Selected for F1000Prime.
9、C. Zhan*#, J. Zhou *, Q. Feng, J. Zhang, S. Lin, J. Bao, P. Wu, M. Luo #, Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively. J Neuroscience (2013). Selected for F1000Prime.
10、C. Zhan, M. Luo, Diverse patterns of odor representation by neurons in the anterior piriform cortex of awake mice. J Neuroscience(2010).
联系方式:
招生招聘：
实验室招聘生物或者医学背景的博士后，特任副研究员和特任研究员，同时欢迎上述背景的学生来本实验室攻读博士学位。
实验室网址：https://zhanlab.ustc.edu.cn/