Author：Wang Juncheng、Qin Su、LI Fudong、Li Sai、Zhang Wei、Peng Junhui、Zhang Zhiyong、Gong Qingguo、Wu Jihui、Shi Yunyu
Abstract:The eukaryotic genome is packed into highly compacted chromatin, the basic unit of which is a nucleosome composed of 147 base pairs of DNA wrapped around the histone octamer. Post-translational modifications along histone N-terminal tails can be recognized by various 'reader' modules. PWWP domain, one type of 'reader' modules, has been identified to recognize H3K36me3 in the peptide and nucleosome context.
http://dx.doi.org/10.1038/cr.2014.38